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Description

What is the use of Viagra?

Viagra is an erectile dysfunction (ED) drug used to treat male erectile dysfunction (ED) and. It helps to treat ED, which is a problem in the male penis. Viagra works by increasing blood flow to the penis, which helps a man get and keep an erection when sexually aroused.

How does Viagra work?

Viagra belongs to a group of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing muscles in blood vessels and increasing blood flow to the penis when a man is sexually stimulated. Viagra also improves sexual function in the presence of a low blood pressure. This helps a man to get and keep an erection.

How to take Viagra?

Viagra should be taken orally about 60 to 100 minutes before engaging in sexual activity, or up to 1 hour before sexual activity. This drug will only help you to get an erection when sexually aroused. You can take Viagra on an empty stomach or with food. Take Viagra about 30 minutes before you plan to have sex. Viagra is to be taken only when needed. It should only be used as needed. Viagra does not increase sexual desire. It only helps you to get an erection if you are sexually stimulated. Viagra will only help you to get an erection if you are sexually aroused. It is to be taken about 1 hour before you plan to have sex. Viagra is to be taken with or without food.

Side effects of Viagra?

The most commonly reported side effects of Viagra are headache, dizziness, upset stomach, diarrhea, and loss of appetite. They are generally mild to moderate and will resolve once you have taken them. If these side effects persist or worsen, consult your doctor. You can also contact a health care provider to report them to a different drugstore.

Viagra increases blood flow to the penis, which causes an erection. The drug is not to be taken with nitrate medications used for chest pain. Viagra will only help you to get an erection if you are sexually stimulated. Viagra does not make you feel better or make you feel better.

Warning and contraindication

Pregnant women should not use Viagra as it could harm their baby. The drug should not be used by children under the age of 18.

These side effects are generally mild to moderate and will resolve once you have taken them.

Nitrate medications used for chest pain, as they are used for high blood pressure. Viagra should not be used by children under the age of 18. There is a small risk of serious cardiovascular complications when taken with certain nitrate medications. Viagra is not to be used to treat chest pain, as it can cause serious cardiovascular problems.

Alcohol is also prohibited by Pregnant women as it can lead to serious health complications.

It was a little embarrassing to go to the doctor, but she was so happy to go. “I was going to go on a long walk and see my GP and take my medicines, but I was so tired and so sleepy and my hands were hurting. So I went back to the chemist and I found I had erectile dysfunction and had to get my medicines back.”

So I was in the chemist and I took one of the little blue pills which were so easy to take, but not for me. The only side effect I noticed was headaches, which were almost impossible to manage. It also helped to relax my throat and chest and make it easier to breathe.

I had an erection at a young age so my GP diagnosed me with erectile dysfunction so that was not something I could do on my own.

So when I got to my doctor I had no idea what erectile dysfunction meant, and I had a headache for weeks. I was so tired and so sleepy and my hands were hurting. My hands were swollen and the pain was so bad I could not get an erection. I was so tired of being worried and anxious all the time. It wasn’t like I could do anything but go on going to the doctor and say, ‘oh, what’s that smell?’

“I started having difficulty with my ejaculation,” she said. “I’m like, ‘Oh, you know what, I’m so tired’, so I went to the chemist and I bought two Viagra. They said it might be a side effect of taking this pill but it didn’t have anything to do with the erectile dysfunction. So I bought a different one and I bought it in the chemist.”

I tried it and the first thing I noticed was that the colour of it was a little brown. I started to see my GP, he said I should not take this, but I had problems with my blood pressure. So he recommended the blue pill, and I had to take one. Then I started having headaches, and they were so bad that I couldn’t sleep. So I took the blue pill and it helped to relax my chest and make it easier to breathe.

After I took the blue pill, I was so tired, I couldn’t sleep and my legs were so weak. I had to get my medicines back and I didn’t feel as I was going to have to go back to the chemist. So I went to the chemist and I found I had erectile dysfunction. I had to go to the doctor. The doctor recommended that I try it and he said that I shouldn’t take it, but I had to go back to the chemist. I had to go to the doctor and he said that I should take it. I had to take a tablet, a pill and an erection. I had to go back to the chemist, and he told me that I couldn’t take it. He told me not to take it and I was told to go back to the chemist. It was so bad that I couldn’t sleep. I had to go back to the chemist and take it.

I was so tired, I couldn’t sleep and my legs were so weak. The doctor told me to take it, and I did. The doctor told me to take it and I did. I had to go back to the chemist.

I couldn’t get an erection, so I started having headaches, and they were so bad that I couldn’t sleep.

The next day, I went to the chemist and I bought the Viagra. At first I thought it was something to do with the ED pills. It was a little blue pill. I took it but I couldn’t get an erection. I tried it with the blue pill, but it worked. It also helped to relax my chest and make it easier to breathe.

Last updated 17 November 2021

At the end of the 90s the pharmaceutical giant Pfizer introduced to an unsuspecting and sexually reticent world. Blasting its way into global culture, the launch of the ‘little blue pill’ changed how the world talked about and improved the sex lives of millions worldwide.

Coined as the second sexual revolution, Viagra changed impotence from a taboo subject that made sufferers doubt their masculinity into a socially-acceptable subject; one with a solution as simple as swallowing a pill.

Carefully protected by patents, sales of the brand name soared, making Viagra one of the most popular drugs of all time. Despite the arrival of competitors, an onslaught of fake online copies and typically high prices, the dominance of Viagra has remained firm for 15 years.

However all that may be about to change. As Pfizer’s global patents begin to expire, questions are being asked about the effect on their supremacy over the ED marketplace. The UK Viagra patent expires in June 2013, opening up the market to legal generic alternatives. What does this mean for the life cycle of the little blue pill?

The story of a patent

Viagra and its meteoric rise to become one of the most recognisable brand-name medications across the world began, like many others, with the fortuitous discovery of an intriguing side effect.

As one hypothesis dies, another emerges

In 1989 a team at Pfizer laboratories in Kent were working on a hypothesis that blocking the enzyme PDE5 would be an effective treatment for symptoms of heart disease, specifically angina. The discovery and synthesis of sildenafil citrate swiftly followed, filed in the manufacturing patent as an experimental compound for heart medication.

Clinical trials investigating high blood pressure and angina began for compound UK-92480, as it was initially referred to. Although the compound was found to have little effect on angina in both phase I and phase II trials, anecdotal evidence from some participants suggested that the drug could stimulate erections. As UK-92480’s prospects of becoming an angina treatment began to fade more volunteers were reporting increased erections, and Pfizer was on the cusp of a significant discovery.

Ian Osterloh, executive director of discovery research at Pfizer remembers the time well in the article “How I discovered Viagra”. He says, “We decided to follow up on these reports to see where it would take us.”

Viagra is born

Where it took them was a series of discovery pilot studies for Erectile Dysfunction (ED), which found that a single daily dose was sufficient to produce an erection. “The initial results were encouraging and showed the drug was much more effective than a placebo,” recalls Ian. In response Pfizer launched an accelerated program of study with 21 clinical trials, involving roughly 4,500 men.

“About 12 years after the project had begun, eight years after the first synthesis of UK-92480 and six years after the first ED pilot study, we finally had enough information to be confident of the best dose, and the drug’s safety and effectiveness.”

Pfizer then filed a new drug application with the Food & Drug Administration (FDA) in America who, following a priority review, approved Viagra to treat ED in the US in 1998. The drug was also licenced for use in the UK the same year. This became the first non-surgical treatment for ED and started a fervour that began with an estimated 40,000 prescriptions in the first week and went on to become one of the most famous drugs worldwide.

Invalid patents open the door for competitors

By the end of 1999, controlling the global market with patents that prevented other drug companies from using not only sildenafil citrate, but even the same class of drug. However this huge piece of the pie was about to be bitten into when a UK ruling opened the doors to competitors.

In 2002, declaring that the scientific knowledge surrounding the key component was already in the public domain. The landmark ruling meant that rival companies would be able to use similar drugs to treat ED, which they quickly leapt on. The following year Viagra’s authority was challenged by the arrival of two ED drugs, and, containing different active ingredients, and respectively.

By 2007 Viagra’s massive share of ED treatment had been affected by both these legal competitors as well as the barrage of counterfeit products and fake copies that filled the internet.